![]() ![]() No exceptional circumstances whatsoever, whether a state of war or a threat of war, internal political instability or any other public emergency, may be invoked as a justification for enforced disappearance. No one shall be subjected to enforced disappearance.Ģ. Have agreed on the following articles: Part I Article 1ġ. Recalling the International Covenant on Economic, Social and Cultural Rights, the International Covenant on Civil and Political Rights and the other relevant international instruments in the fields of human rights, humanitarian law and international criminal law,Īlso recalling the Declaration on the Protection of All Persons from Enforced Disappearance adopted by the General Assembly of the United Nations in its resolution 47/133 of 18 December 1992 ,Īware of the extreme seriousness of enforced disappearance, which constitutes a crime and, in certain circumstances defined in international law, a crime against humanity,ĭetermined to prevent enforced disappearances and to combat impunity for the crime of enforced disappearance,Ĭonsidering the right of any person not to be subjected to enforced disappearance, the right of victims to justice and to reparation,Īffirming the right of any victim to know the truth about the circumstances of an enforced disappearance and the fate of the disappeared person, and the right to freedom to seek, receive and impart information to this end, Having regard to the Universal Declaration of Human Rights, PreambleĬonsidering the obligation of States under the Charter of the United Nations to promote universal respect for, and observance of, human rights and fundamental freedoms, All rights reserved.Entry into force: 23 December 2010, in accordance with article 39(1) which reads as follows: “This Convention shall enter into force on the thirtieth day after the date of deposit with the Secretary-General of the United Nations of the twentieth instrument of ratification or accession.”. At multivariate analysis, delayed/late PJIs were significantly associated with failure (OR = 12.51 95% CI 1.21-129.63, p = 0.03).ĭAIR represents an effective strategy for the treatment of early PJIs in spite of short course of antibiotic therapy.Īntibiotics Debridement Implant retention Prosthetic joint infection.Ĭopyright © 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. ![]() Sixteen (76%) patients were cured after a median follow-up of 2197 days (IQR, 815-2342 days), while 5 (24%) experienced failure. The median duration of antibiotic treatment after surgery was 63 days (IQR, 53-84 days). Median time from PJI-related symptoms onset to implant revision surgery was 12 days (IQR, 7-20 days). These were classified as early PJIs in 76% cases, delayed in 19% and late in 5%. Twenty-one patients (45%) aged 71 years were treated with DAIR for hip (62%) and knee (38%) PJIs. We performed a retrospective analysis of prospectively collected data of all hip and knee PJIs consecutively diagnosed at Quadrante Orthopedic Center, an Italian orthopedic hospital highly specialized in prosthetic surgery, from Januto January 1, 2019, and we analyzed those treated with DAIR.įorty-seven PJIs occurred after 5102 arthroplasty procedures. The secondary aim is to identify risk factors for DAIR failure. The primary aim of this study is to report the outcome of DAIR in patients with hip and knee PJIs receiving short course of antibiotic therapy. ![]() However, reported success rates and predictors of DAIR failure vary widely. Debridement, antibiotics and implant retention (DAIR) is an attractive treatment option for prosthetic joint infections (PJIs).
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